Rahim Yar Khan is the last district of Punjab province and is located at the junction of three provinces of Pakistan i.e. Sindh, Punjab and Balochistan. Rahim Yar Khan is named after one of the grandsons of Nawab of Bahawalpur. It is one of the top districts of Pakistan in agriculture production and revenue generation. It is linked by air to the other parts of the country and is situated on the main railway line and National Highway linking Karachi, Lahore and Peshawar & CPEC Motorway.
The Sheikh Zayed Medical College Rahim Yar khan was established in March 2003 as a self-financing medical institute. In 2008, Government of Punjab abolished self-finance seats in medical and dental institutions of the Punjab and converted all these seats into open merit seats. Prof. Dr. Eice Muhammad was its first Principal while Prof. Dr. Tariq Ahmed is its present Principal.The SZMC/H is a tertiary healthcare institution striving hard towards excellence in teaching and training of Health Professionals and has become a role model of medical education and patient care. With the completion of new college building in 2017, the basic sciences departments and administration of the college has been shifted to this new Campus which is located in the east of Sheikh Zayed Hospital.